ACS

Sessions

Analytical Chemistry
Biochemical Technology
Chemistry and the Law
Chemical Safety
Computational Chemistry
Education
Entrepreneurship
Environmental Chemistry
Ethnobotanical Drugs
Food Chemistry
Fuel Chemistry
Inorganic/Organometallic Chemistry
Medicinal Chemistry
Nanomaterials
Natural Products
Nuclear Chemistry
Nuclear Magnetic Resonance
Organic Chemistry
Pharmaceutical Sciences
Physical Chemistry
Polymer Chemistry
Process Organic Chemistry
Renewables
Solar
Women Chemists

Western Regional Meeting Technical Program Details

PACS is now closed.

Schedule of Sessions

Analytical Chemistry

Session 1: Analytical Chemistry Applications in Electronic Manufacturing (Lisa Milstein)

The presentations will feature applied analytical techniques to materials (e.g. thin films, batteries) and manufacturing in the semiconductor and PV industries.

SPEAKERS

  1. H. E. Gotts, "Survey of Analytical Techniques Useful for Thin Film Material Evaluation in High Technology Applications"
  2. C. Mckenna, V. Thirumala, "Characterization of Precursors used in Semiconductor Manufacturing using a diverse set of Analytical Techniques"
  3. L. S. Milstein, P. L. Clancy, H. E. Gotts, "Analytical Characterization of Thin Films for ALD"
  4. S. A. Myers, H. E. Gotts, "Photovoltaic Materials Defect Characterization Techniques"
  5. P. Voelker, "Trace Degradation Analysis in Li-ion Battery Electrolytes"

Session 2: Best Practices of HPLC in Pharmaceutical Analysis (Michael Dong, CJ Venkatramani)

The advent of sub-2 micron packings with ultra-high-pressure LC (UHPLC) and its successful commercialization in recent years has resulted in significant advancements in modern HPLC in terms of speed, efficiency, precision and sensitivity. This, in conjunction with novel stationary phases and automated method development software, has extended the capabilities of HPLC in pharmaceutical development for the analysis of trace impurities.

The symposium will open with best practices of UHPLC in pharmaceutical analysis with special emphasis on its benefits, potential issues and QC compatibility. This will be followed by presentations on HPLC method development and optimization strategies using novel software tools using simulation, peak tracking and design of experiments approaches. Other presentations will focus on the analysis of trace impurities which are potentially genotoxic and the advancements in column technology with impacts on biopharmaceutical analysis (e.g., monoclonal antibodies, mAb). The presentation on 2D-LC-MS will highlight challenges encountered by pharmaceutical industry towards co-eluting impurities with active pharmaceutical ingredients.

INVITED SPEAKERS

  • Michael Dong (Genentech) "Best Practices of Ultra-high pressure liquid chromatography (UHPLC) in Pharmaceutical Analysis"
  • Dan Prudhomme (Gilead) "HPLC Method Development Approach Using QbD"
  • Xiaodong Liu (ThermoFisher) "Mixed-Mode Chromatography and Its Uses in Pharmaceutical Analysis"
  • CJ Venkatramani (Genentech) "Applications of Two-dimensional Liquid Chromatography Mass Spectrometry in Pharmaceutical Analysis"

Session 3: Analytical: Mass Spectrometry: Qualitative Applications (Bill Fitch)

From the time J.J Thompson built a lab instrument to study isotopes and electrons, the mass spectrometer has been a powerful tool for determining the structures of atoms and molecules. We illustrate just a few of these areas.

INVITED SPEAKERS

  • Bill Fitch, Theresa Mary McLaughlin (Stanford) "Application of MS for determining the site where a drug alkylates hemoglobin"
  • Prakash Bolledula (Theravance) "Structure determination of drug metabolites and natural products"

Session 4: Analytical: Mass Spectrometry: Quantitative Applications (Bill Fitch)

Mass spectrometry is an exquisitely sensitive and specific tool for quantitative analysis. Modern instruments can be found in laboratories pursuing drug research and development, forensics, clinical chemistry, environmental analysis, archaeology, food safety, space exploration... We illustrate just a few of these areas.

INVITED SPEAKERS

  • J. Michael Moldowan, Jeremy Dahl (Biomarker-Inc) "GCMS of diamondoids-application to developing unconventional hydrocarbon production"
  • Peyton Jacob III, (UCSF) "Tobacco biomarkers"

ORGANIZERS

Michael Dong   
Senior Scientist   
Genentech   
CJ Venkatramani   
Scientist   
Genentech   
Bill Fitch   
Visiting Professor   
Biomaterials & Advanced Drug Delivery   
Stanford University   
Lisa Milstein   
R&D Scientist   
Air Liquide Electronics   


Biochemical Technology

Session 1: Advances in Upstream Bioprocessing (Claire Komives)

This session will highlight recent advances in bioreactor processing and biological conversion for production of chemicals, drugs, and biofuels. Topics relevant to this session may include, but are not limited to: cell-free systems for biosynthesis; enzyme engineering for green chemistry; metabolic and cell engineering for improved fermentation and cell culture processes; integrated fermentation-separation processes; scale-up and scale-down technologies for process optimization; and engineering for sustainability. Papers describing progress in the development of continuous bioprocessing are particularly encouraged.

Session 2: Advances in Downstream Bioprocessing (Jonathan Coffman)

This session will emphasize new developments in downstream processing of biopharmaceuticals, enzymes and biochemicals. Of particular interest are advances in continuous bioprocessing, including simulated moving bed chromatography, single pass tangential-flow filtration, continuous aqueous two-phase extraction, and other methods. Also of interest are improved strategies for formulation of protein and other bioproducts for stability and increased bioavailability.

ORGANIZERS

Claire Komives   
Professor   
Chemical & Materials Engineering   
San Jose State University   
Jonathan Coffman   
Director of Engineering   
Boehringer-Ingelheim   


Chemistry and the Law

Session 1: Where Chemistry Meets the Law: The America Invents Act in Your Business

Session 2: Where Chemistry Meets the Law: Alternative Careers for Chemists

ORGANIZER

Sandra Thompson   
BuchalterNemer, A Professional Corporation   


Chemical Safety Session

Session: Changes in Laboratory Waste Management: The Revised Lab Standard and GHS

Significant changes in the OSHA Laboratory Standard as well as the ongoing implementation of GHS labeling and classification of chemicals have resulted in challenges for laboratories from the perspective of Chemical Hygiene Plan revisions, training, and information for employees. This session will help attendees learn about what they need to do to implement the new requirements and provide some insight into what it means for senior management, principal investigators, Chemical Hygiene Officers, and others involved in laboratory operation and safety.

ORGANIZER

Russ Phifer   
WC Environmental, LLC   
Debbie Decker   
UC Davis   


Computational Chemistry

Session: Modern Computational Chemistry

This session will highlight the diverse capabilities of modern computational chemistry. Talks will describe the use of quantum chemistry, molecular mechanics, cheminformatics, and related tools to problems in catalysis, energy, biochemistry, drug discovery, and other domains. The session will consist primarily of invited talks with submitted abstracts included as space allows.

Presiders: Stephen Boyer, Jed Pitera

SPEAKERS

  1. Mahnaz Firouzi (Wilcox Lab, Stanford) "Gas Permeability and Klinkenberg Effects in Carbon Micro and Mesopores"
  2. Guenter Grethe (-) "International Chemical Identifier for Reactions" (RInChI)
  3. Marc Adler (Elan) "Improved Ligand Binding Energies Derived from Molecular Dynamics: Replicate Sampling Enhances the Search of Conformational Space"
  4. J.W. Feng (Genentech) "Interactive Shape and Pharmacophore Similarity Search Enabled by GPUs"
  5. Hans Horn (IBM) "Organic Acid-Catalyzed Polyurethane Formation via a Dual-Activated Mechanism: Unexpected Preference of N-activation over O-activation of Isocyanate"
  6. Siegfried Leung (Jacobson Lab, UCSF) "Computer-aided Design of Permeable Cyclic Peptides"
  7. Graham McGibbon (CSD Labs) "Improving the Prediction of Drug Disposition in the Brain with Mechanistic Models of Brain Penetration Characteristics"
  8. Julien Panenetier (LBL) "Understanding the Electronic Structure of Cobalt-Dithiolene H2 Evolution Catalysts"
  9. Nathan Luehr (Martinez Lab, Stanford) "Interactive ab initio Molecular Dynamics"
  10. Michael Keiser (Seachange) "Predicting Drug Secondary Pharmacology and Mechanistic Targets"
  11. Diwakar Shukla (Pande Lab, Stanford) "Proteus Among Proteins: A Collection of Short Stories About Conformational Changes in GPCRs and Kinases"
  12. Jerome Nilmeier (Lawrence Livermore National Laboratory) "Automated Catalytic Site Detection"

ORGANIZERS

Stephen Boyer   
IBM Almaden Research Center   
Jed Pitera   
IBM   


Education

Session 1: The Two-Year College: A Legitimate Pathway for Underrepresented Minorities Pursuing STEM Careers

The Mission of the ACS Committee on Minority Affairs (CMA) is "to advance ethnic and racial diversity and inclusion in ACS and the broader chemistry enterprise." For this purpose, during its 20th anniversary, CMA sponsors a session in which the community college shares the efforts and struggles in educating and impacting the largest and most diverse group in the U.S. Higher Education Enterprise. Topics will focus on strategies to increase success, recruitment and retention, to refine the delivery of chemistry lectures to culturally diverse populations and to introduce laboratory research in the chemical sciences.

This session will be limited to invited speakers.

ORGANIZERS

Onofrio Gaglione   
College of Southern Nevada   
Professor-Emeritus NYCCT (CUNY)   
Armando Rivera-Figueroa   
Associate Professor   
East Los Angeles College   

Session 2: High School and Undergraduate Education

ORGANIZERS

Harry Ungar   
Cabrillo College   
haungar@cruzio.com   
Jeanette Medina   
Cañada College   
medinaj@smccd.edu   


Entrepreneurship

Session 1: Business Considerations for Science Entrepreneurs

This session will provide considerations for starting (or working in) a small science-based business. Topics will include how to balance the needs of research, capital and development; intellectual property and other legal considerations; business plans; and incorporation considerations. Resources offered by ACS and other organizations will also be covered.

Session 2: Models and Roles of Incubators

The needs of a science-based start-up may be substantial, including expensive instrumentation, specialized laboratory space, permits and other infrastructure. Many science-based start-ups are taking their initial steps within incubators which are rapidly expanding in the bay area, and in other locations. Incubators can be particularly useful for meeting those needs and for providing support from experts in many disciplines. This session will examine the different designs and business models of incubators including physical, operational and technical support offered, as well as the expectations and commitments for entrepreneurs who get their start in an incubator.

Session 3: Sources of Funding for Entrepreneurs

This session will explore different sources of funding for start-ups and emerging companies. Areas to be discussed range from the emerging area of crowd-funding and how to obtain a Small Business Innovation Research (SBIR) grant to funding practices of angels and venture capitalists. A panel discussion will provide insight into the challenges and prospects of funding a small science-based business.

Session 4: True Stories of Entrepreneurs

The entrepreneurship program will conclude with presentations from entrepreneurs who will discuss their experiences and lessons learned as scientists starting a small business. Companies discussed will range from one started in the 70's to some less than a year old, and provide true stories from a wide range of science, services, products and visions.

These sessions will be limited to invited speakers.

ORGANIZERS

Bonnie Charpentier   
Vice President   
Regulatory and Quality   
Metabolex, Inc.   
Natalie McClure   
Senior Vice President   
Product Development   
Adamas Pharmaceuticals   
Joe Sabol   
Chemical Consultant   
Mick Hurrey   
Gilead Sciences   


Environmental Chemistry

Session: Hydraulic Fracturing in California: Environmental Issues with the Largest Shale Oil Formation in the US

This symposium will contain the latest information on hydraulic fracturing (fracking) including the technical challenges, environmental effects, and political and regulatory climate. Existing shale plays in the U.S. will be discussed and particular emphasis will be placed upon California's Monterey Shale formation. Significant environmental concerns have been raised at fracking locations throughout the U.S. The injection of millions of gallons of drilling fluids with toxic additives in boreholes extending for miles to crack the shale and release oil and methane has led to claims of contaminated water supplies, releases of chemically contaminated flowback fluids, air pollution, increased greenhouse gas emissions, and induced earthquakes.

Click here for full Call for Papers.

Presiders: Donna Drogos and Ean Warren

SPEAKERS

  1. Paul Rosenfeld "Air Dispersion Modeling of Volatile Organic Emissions from Multiple Natural Gas Wells in Decatur, Texas"
  2. Julie Sueker (ARCADIS-US) "Isotopic Forensic Techniques for Methane Source Discrimination"
  3. Matthew Becker (CSU, Long Beach) "Protection of Groundwater Resources in the Vicinity of Hydraulic Fracturing Operations: Lessons from New York State and the Marcellus Shale"
  4. Mark Zeko/ Emily Vavricka "Hydraulic Fracturing and the Impacts to Groundwater and Water Quality: The Importance of a Monitoring Program"
  5. Andrew Barron (Rice University) "Analysis, Treatment and Tracing of Frac and Produced Water"
  6. Carl Fisher (Fisher Thermo Scientific) "Analysis by Ion Chromatography of Fracking Flowback Water From the Marcellus Shale Using In-line Conductivity and Automated Dilution"
  7. Donald Carpenter (ARCADIS US) "Optimized Geochemical Modeling of Produced Fluids Provides Important Insight into NORM-Related Issues"
  8. William Ellsworth (U. S. Geological Survey) "Hydraulic Fracturing, Wastewater Injection and Unintended Earthquakes"
  9. Mark Nechodom (California Department of Conservation) "The Science and Politics of Hydraulic Fracturing in California"
  10. Kyle Ferrar "Advocating for Safe Oil and Natural Gas Extraction Policies; an Overview of FracTracker as a Mechanism for Overcoming the Barriers to Scientific Advocacy and Community Engagement"
  11. Earl Hagström (Sedgwick) "Hydraulic Fracking and the Battle Over Beneficial Water Use in California, the Next Phase of Fracking Litigation in California"
  12. David Miller "How API's Shale Gas Standards and Best Practices support Sustainable Shale Gas Development"
  13. Panel Discussion: David Baker (SF Chronicle) David Miller, Earl Hagström & Mark Nechodom
ORGANIZERS
Ean Warren   
Hydrologist   
U.S. Geological Survey   
Donna Drogos   
Division Chief   
Alameda County Environmental Health   


Ethnobotanical Drugs

Session: Ethnobotany as Inspiration for Drug Discovery and Development

The issues facing researchers in the medicinal plant/herbal areas in developing commercial products in the US consumer health care and pharmaceutical markets will be addressed over a range of talks in this session. The discovery and development of SP-303/crofelemer/ fulyzaq, a recently approved botanical drug, will be used as a relevant example of the process necessary to be successful.

INVITED SPEAKERS

  • Steven King "The development of the first oral botanical drug FULYZAQ: connecting ethnobotany, conservation, biocultural diversity, global public health and indigenous knowledge"
  • Joe Betz "Scientific and Regulatory Challenges in the US Botanical Marketplace"
  • Tom Carlson "Crofelemer: a Novel Antidiarrheal Medicine from the Amazon Rainforest-Mechanism of Action and Clinical Applications"
  • Michael Tempesta "The Discovery of SP-303 (Crofelemer/Fulyzaq), a Novel Polyphenol isolated from Croton lechleri"
  • Leslie Gunitilaka "Traditional Medicine Inspired Drug Discovery for some Modern Day Diseases"

This session will be limited to invited speakers.

ORGANIZER

Michael Tempesta   
Director   
TerraPharm   


Food Chemistry

Session: Many Flavors of Food Chemistry

ORGANIZER

Sara Risch   
POPZ, Inc.   


Fuel Chemistry

Session: Petroleum and Bio-Fuel Analysis

ORGANIZERS

Michael Cheng   
Chevron   
Don Crider   
Chevron   


Inorganic/Organometallic Chemistry

General Session

Presider: Prof. Lionel Cheruzel

SPEAKERS

  1. Isaac Yonemoto (J Craig Venter Institute) "Insights in Enzyme Modification for Renewable Solar Hydrogen"
  2. Nikolay Kornienko (UC Berkeley) "Visible Light Photoredox Catalysis: Selective Reduction of Carbon Dioxide to Carbon Monoxide by a Nickel N-heterocyclic Carbene-isoquinoline Complex"
  3. Jose Martinez (UC Santa Cruz) "Synthesis and Comparison of Two Tripodal Ligands Bearing Nitrogen and Sulfur Donors and Their Coordination With Ru(II)"
  4. Kathleen Lee (UC Davis) "Synthesis, Crystal Structure, and Transport Properties of a New Li-containing Layered Material, LixSn3-xAs2"
  5. Lionel Cheruzel (San Jose State University) "Selective Light-driven Aerobic Hydroxylation of C-H Bonds using Hybrid P450 Biocatalysts"

Session: Small-Molecule Activation and Redox Catalysis with Metal Complexes and Surfaces

Presider: Prof. Matt Kanan

  1. Louise Berben (UC Davis) "Electrocatalytic Reduction of H+ and CO2 by a Series of Iron Carbonyl Clusters"
  2. Alan Heyduk (UCI) "Using Redox-active Ligands to Promote Multi-electron Reactivity at Electrophilic Metal Centers"
  3. Joshua Figueroa (University of California, San Diego) "Group 10 Metal-Mediated N-O Bond Activation"
  4. Matt Kanan (Stanford) "Two-step Electroreduction of CO2 to Ethanol Catalyzed by Oxide-derived Metal Nanoparticles"

ORGANIZER

Matt Kanan   
Assistant Professor   
Department of Chemistry   
Stanford University   


Medicinal Chemistry

Session: Recent Advances in Medicinal Chemistry

Presiders: Al Garofalo, Yingzi Isabella Xu

SPEAKERS

  1. Alex Muci (Cytokinetics) "Discovery of the First Small Molecule Activators of Cardiac Myosin for the Treatment of Heart Failure"
  2. Eda Canales (Gilead) "Hit-to-Lead Optimization of a Pan-Genotypic Tetrahydroquinoline Scaffold for the Treatment of HCV"
  3. ZhaoZhong Jia (Pharmacyclics) "Small Molecule BTK Inhibitors: an Update From Pharmacyclics"
  4. Jun Liang (Genentech) "Identification of Potent, Selective and Orally Bioavailable TYK2 Inhibitors for Psoriasis and Inflammatory Bowel Diseases (IBD)"
  5. Gina Xiaojing Wang (Genentech) "Discovery of Potent and Bioavailable Pim Inhibitors for Multiple Myeloma"
  6. Adam Hughes (Theravance) "Discovery of Muscarinic Acetylcholine Receptor Antagonist and Beta-2 Adrenoceptor Agonist (MABA) Dual Pharmacology Molecules"
  7. Mark Zak (Genentech) "Discovery of NAMPT Inhibitors with Favorable Physicochemical Properties as Potential Treatments for Cancer"
  8. Tim Owens (Principia) "Increasing Target Residence Time in Drug Discovery; Optimization via Covalent Reversible Interactions"
  9. Yang Liu (Anacor) "The Potential of Boron-containing Small Molecules in Medicinal Chemistry"
  10. Dustin McMinn (Onyx) "Targeting the Immunoproteasome"
  11. Julio Medina (Amgen) "Inhibiting Protein-Protein Interactions"
  12. Albert Garofalo (Redwood Bioscience) "Hydrazino-iso-Pictet-Spengler Ligation: A New Method for the Generation of Stable ADC's"
  13. Jun Wang (UCSF) "Rational Design of Inhibitors Targeting the Drug Resistant Influenza A Virus M2 (A/M2) Proton Channel"
  14. Joe Olechno (Labcyte) "Liquid Handling and Dilutions Profoundly Affect Biological Assays"
  15. Megan Bolitho (USF) "Optimizing Synthetic Access to the Quorum Sensing Substrate S-Ribosylhomocysteine (SRH)"
  16. Nicholas Skelton (Genentech) "Adventures With AKT: Small Molecule Inhibition and Mechanism of Activation"

ORGANIZERS

Al Garofalo   
Redwood Biosciences   
Yingzi Isabella Xu   
BaySide Chem.   


Nanomaterials (organic)

Session: Functional Carbon-Based Nanomaterials

Presider: Professor Felix Fischer

SPEAKERS

  1. Timothay Hom (San Jose State University) "Synthesis of Verdazyl Substituted Triphenylamine Derivative"
  2. Francesca Maria Toma (University of California, Berkeley) "Decacyclene-Based Materials: A New Frontier of Renewable Energy and Optoelectronic Research"
  3. Evan Sarina (UC Davis) "Conclusion to the 22 Year Mystery of the Fullerene (C60) Pentane Solvate Structure"
  4. Michael Haley (University of OREGON) "Indenofluorenes - a New Class of Electron-Accepting Materials"
  5. Mengyao Gao (Beijing University) "Investigation on Inhibition of Polysulfides Dissolved into Electrolyte Using Porous Carbon in Rechargeable Lithium-sulfur Batteries"
  6. Hanqing Pan (CSU, Long Beach) "Heat-induced Coarsening of Gold Nanoparticles on Grapheme"

ORGANIZER

Felix Fischer   
Assistant Professor of Chemistry   
University of California, Berkeley   


Natural Products

Session 1: New Technologies in Natural Products Discovery

Increasingly, natural products research is expanding beyond the scope of traditional isolation and structure elucidation to incorporate a host of new technologies from mathematically intensive computational modeling to high-throughput genomics. The aim of this session is to highlight some of these new technologies as they apply to natural products research, and to present examples of new insights being brought to the field using these techniques.

Session 2: Organic Chemistry Approaches to Natural Products Development

As the number of natural product scaffolds in the literature reaches maturity, attention is turning towards methods and mechanisms to exploit this pool of chemical diversity for biomedical applications. This session will present lectures surrounding the theme of natural products development, from biosynthetic engineering to the synthesis of natural product mimics, and the understanding of natural strategies for the design of better drugs.

Presiders: Roger Linington and Tara Amagato

SPEAKERS

  1. Kerry McPhail (Oregon State University) "Strategies to Investigate Microbial Natural Products from Deep-sea Hydrothermal Vent"
  2. Robert O'Brien (Stanford University) "New Analogs of 6-Deoxyerythronolide B and Erythromycin A Produced by Precursor Directed Biosynthesis and in Vitro Reconstitution of the 6-Deoxyerythronolide Synthase"
  3. Jacob Winnikoff (Stanford University) "Use of High Content Molecular Networks to Profile and Quantitate Marine Cyanobacterial Metabolomes"
  4. Paul Boudreau (Scripps Institution of Oceanography) "Application of Overlapping Techniques to Profile a Well-studied Cyanobacterial Strain Affords a Richer Understanding of its Metabolome"
  5. Dean Tantillo (University of California, Davis) "Walking in the Woods with Quantum Chemistry - Studying Natural Product Biosynthesis with Computational Chemistry"
  6. Chambers Hughes (Scripps Institution of Oceanography) "Thiol-based Probes for the Discovery of Electrophilic Natural Products from Marine Bacteria of the Genus Salinispora
  7. Anne Murray (UC Berkeley) "Inhibitory Mechanisms of Tannins on the Enzyme Tyrosinase
  8. Laura Sanchez (University of California, San Diego) "Mass Spectrometry Based Investigations of Cheese-Derived Natural Products"
  9. Scott Lokey (UC Santa Cruz) "New Chemical Methods for the Selective, on-resin N-Methylation of Cyclic Peptides to Generate Compounds with Improved Membrane Permeability
  10. Mohamed Donia (UCSF) "Natural Products from the Human Microbiota
  11. Kelvin Billingsley (San Francisco State University) "Lead Diversification Through a Prins-Driven Macrocyclization Strategy: Application to Functionalized B-Ring Bryostatin Analogues"
  12. Jared Moore (University of California, Davis) "Enantioselective Synthesis of (R)-Homocitric Acid Lactone-1,2-13C2"
  13. Taro Amagata (San Francisco State University) "Exploring Class III HDAC Inhibitors from Marine Sediment-Derived Actinomycetes Using an HDAC-Based Yeast Screening Method"
  14. Patrick Still (UC Santa Cruz) "Alkaloids from Microcos paniculata L. with Cytotoxic and Non-competitive Nicotinic Receptor Antagonistic Activities: The Transition from Terrestrial Plants to Marine Organisms"
  15. Ryan Pemberton (UC Davis) "Probing Terpene Enzymatic Functionality and the Inherent Dynamical Preferences in Carbocation Rearrangements"
 

ORGANIZERS

Roger Linington   
Assistant Professor   
Chemistry & Biochemistry Department   
University of California, Santa Cruz   
Taro Amagata   
Assistant Professor   
Department of Chemistry & Biochemistry   


Nuclear Chemistry

Session: Symposium in Honor of Professor Darleane Hoffman

This session is being held to honor the life and career of Professor Darleane C. Hoffman. Her pioneering research in nuclear chemistry earned her a position as the first female division leader at Los Alamos National Laboratory and subsequently a position as a full professor at the University of California at Berkeley. The results of her work added new insights into the process of nuclear fission, the existence of heavy elements in nature, and chemical properties of the heaviest elements. The keynote address by Professor Hoffman is called "Sixty-five years as a nuclear chemist - A retrospective view". This will be followed by presentations from former colleagues and students describing Professor Hoffman's contributions, both scientific and for the advancement of women in science.

This session will be limited to invited speakers.

ORGANIZER

Dawn Shaughnessy   
Chemical Sciences   
Lawrence Livermore National Laboratory   


Nuclear Magnetic Resonance

Session: Recent Advances and Applications in NMR Spectroscopy

Biomolecular NMR has been an indispensable tool in problem-solving efforts in structural biology, biochemistry, microbiology, physiology, and drug discovery. This session will highlight cutting-edge applications in whole cells and macromolecular systems as well as new advances in methods development. The session will consist of invited talks and selected talks from submitted abstracts as space allows.

INVITED SPEAKERS

  • Lynette Cegelski (Stanford)
  • Krish Krishnamurthy (Agilent)
  • Rachel Martin (UC Irvine)
  • Rie Nygaard (Stanford, Kobilka/Cegelski Labs)
  • Carrie Partch (UC Santa Cruz)

ORGANIZER

Lynette Cegelski   
Assistant Professor   
Department of Chemistry   
Stanford University   


Organic Chemistry

General Session

Presider: Matthew Duncton

SPEAKERS

  1. Beth Kochly (Mills) "Effect of Ionic Liquid Cosolvent on the Methanolysis of Pivaloyl Triflate"
  2. Thanh Ngoc Le (SJ State) "Water Soluble Verdazyl Radicals Synthesized From Aldoses"
  3. Makan Kaviani-Joupari (CSU Long Beach) "Multiplying the Catalytic Output of Reactions Through Bifunctional Substrates"
  4. Ihsan Erden (SFSU) "An Efficient Approach to the Total Synthesis of Acylfulvenes, a Class of Potent Antitumor Agents"
  5. Kellan Lamb (UC Davis) "Asymmetric Synthesis of 2,3-Dihydrobenzofurans via Rh(II) Catalyzed C-H Insertions"
  6. Nicolas Ball-Jones (UC Davis) "Cation Stabilizing Strategies for Sc-catalyzed Enantioselective [3+2] Carbocycle Annulations with Allylsilanes"
  7. Matthew Duncton (Rigel) "Synthesis of trans-2-(trifluoromethyl)cyclopropanes via Suzuki Cross-Coupling Reactions with a MIDA Boronate"

Session 1: Recent Advances in Organic Chemistry

Presider: Thomas Maimone

SPEAKERS

  1. Javier Read de Alaniz (UCSB) "New Advances in the Construction of C-N and C-O bonds for Organic Synthesis"
  2. Dean Toste (UC Berkeley) "Asymmetric Catalysis with Cations and Anions"
  3. Jane Wang (Caltech) "Cyclopropanation via Carbene Transfer to Olefins Catalyzed by Cytochrome 'P411'"
  4. Armen Zakarian (UCSB) "Total Synthesis and Glucokinase Activating Properties of Tatanans A-C"

Session 2: Cope Scholar Symposium in Honor of Professor Sarah Reisman: Advances in Total Synthesis

Presider: Thomas Maimone

SPEAKERS

  1. Ryan Shenvi (Scripps Research Institute) "Chemical Synthesis of Secondary Metabolites"
  2. Chris Beaudry (Oregon State) "Synthesis of Natural Products with Conformational Chirality"
  3. John Wood (Baylor University) "Recent Progress in the Synthesis of Complex Natural Products"
  4. Sarah Reisman (Caltech) "Natural Product Synthesis: A Platform for Chemical Discovery"

ORGANIZER

Thomas Maimone   
Assistant Professor of Chemistry   
University of California, Berkeley   


Pharmaceutical Science

Session 1: Solid State Properties in Drug Development: Challenges for Drug Substances and Dosage Forms

ORGANIZERS

Dave Toman   
Mike Brandl   


Physical Chemistry

Sessions 1 and 2: Physical Chemistry for a Sustainable Future

Presiders: Hendrik Bluhm, Musahid Ahmed & Oliver Gessner

SPEAKERS

  1. Craig Taatjes (Sandia-CRF) "Autoignition Chemistry of Oxygenated Molecules: Linking Biofuel Development with Advanced Engine Combustion"
  2. Chris Cappa (UC Davis) "Secondary Organic Aerosol Phase and Impacts on Heterogeneous Oxidation"
  3. Hugo Destaillats (LBNL) "Molecular Understanding of Self-Cleaning and Depolluting Photocatalytic Processes on Urban Surfaces"
  4. Jin Zhang (UC Santa Cruz) "Dynamic Perspective on Optimizing Charge Transfer and Transport in Quantum Dot Sensitized Metal Oxide Nanostructures for Light Energy Conversion"
  5. Alexander Ayzner (Stanford) "Sub-50 fs Electron Delocalization Dynamics via Resonant Auger Spectroscopy: The Case of Oriented Organic Semiconductor Interfaces"
  6. Wenkai Zhang (Stanford PULSE Institute) "Femtosecond X-ray Spectroscopy Studies of Electronic Excited States in Coordination Chemistry"
  7. Munira Khalil (U Washington) "Probing Energy Transfer and Structural Evolution During Ultrafast Charge Transfer Process"
  8. David Prendergast (LBNL) "Revealing the Electronic Structure Governing Energy Transfer Through Simulated Spectroscopy"
  9. Tanja Cuk (UC Berkeley) "The Role of Fast Charge Carrier Dynamics at the Catalyst/Reactant Interface: Water Oxidation on Transition Metal Oxide Surfaces"
  10. Willliam Chueh (Stanford) "Nonstoichiometric Oxides Surfaces Far From Equilibrium"

ORGANIZERS

Hendrik Bluhm   
Lawrence Berkeley National Laboratory   
Musahid Ahmed   
Lawrence Berkeley National Laboratory   
Oliver Gessner   
Lawrence Berkeley National Laboratory   


Polymer Chemistry

Session 1: The role of 14Silicon in Polymer Chemistry and Materials Science

The current world-wide sales of polysiloxanes or silicones is approximately $10 billion per year. Many types of silicon compounds are used in polymer chemistry and include silanes, siloxanes, silsesquioxanes, and silicates. Materials utilizing these compounds vary greatly in type and application. This symposium will cover recent technological advancements in silicon-containing polymers and materials containing silicone. Example topics can include synthesis of new silicone polymers and copolymers, Silsequioxanes in polymer chemistry, and the science and technology of elastomers, gels, fluids, pressure sensitive adhesives, biomedical products, electronic encapsulants, personal care products, and surface and interfacial agents.

Session 2: Polymers at the Interface with Biology

Recent decades have seen a tremendous growth of research at the interface of polymer and materials science and biology. New biomaterials concepts are emerging from our understanding of the interactions between materials and biological systems. This symposium will showcase exciting new research at the interface between polymer science and biology. Topics can include the design and synthesis of polymeric materials for biomedical applications, biohybrid polymers in materials applications, polymers in infectious disease, immunology, targeted delivery, tissue engineering, and imaging applications.

ORGANIZERS

Jeffrey G. Linhardt   
Google   
Joseph M. Mabry   
Air Force Research Laboratory   
Propulsion Materials and Applications   
Professor Sarah Heilshorn   
Materials Science & Engineering Department   
Stanford University   


Process Organic Chemistry

Session: Innovation in Process Chemistry

Presider: Michael Humora

SPEAKERS

  1. Theresa Humphries (Genentech) "Process Development of PI3K Inhibitor GDC-0980"
  2. George Yiannkouros (Irix) "A New, Short, Versatile, Scalable, Cost Effective, and General Synthesis for All Prostanoids has Been Achieved in our Laboratories"
  3. Mohammed Masjedizadeh (Principia Biopharma and Roche) "Process Optimization and Scale up Activities for Preparation of an HCV NS5B Polymerase Inhibitor"
  4. Mike Dappen (Elan) "ELND006: Process Chemistry Improvements to the Key Enantioselective Step"
  5. Michael Humora (Biogen) "Early Process Research Strategies: Evaluating Multiple Routes with Multiple Suppliers for Addressing a Key Feature of a Target Molecule"
  6. Giorgio Bertolni (Infa) "From Few Grams to Multi Tons. Some Tips"

ORGANIZER

Michael Humora   
Biogen Idec   


Renewables

Session 1: Biomass: Value-Added Commodity Chemicals from Biofuel Platforms (Marty Mulvihill)

Presider: Marty Mulvihill

SPEAKERS

  1. Marty Mulvihill (UC Berkeley) "Using the Tools of Green Chemistry and Biomimicry to Identify new Functional BioBased Chemicals for Industrial Applications"
  2. Abraham Ringer (UC Berkeley) "Biobased Chemicals and Fuels in Historical and Economic Perspective"
  3. Bryan Yeh (ZeaChem) "Cost Effective Production of Cellulosic Two and Three Carbon Molecules Using the ZeaChem Process"
  4. Lisa Anderson (UC Davis) "Small Molecule Modulators of Lipid Production in Microalgae and NMR Spectroscopic Analysis of Lipids for Biofuel Applications"

Session 2: Renewables: Chemicals and Polymers (Marc Foster and Bill Orts)

Presider: Marc Foster

SPEAKERS

  1. Allison Flynn (Lapol) "Towards a PLA for Durable Goods"
  2. Xiaofeng Liu (UC Santa Barbara) "Extended Donor-acceptor Alternating Narrow Band-gap Molecules for Organic Photovoltaics: Bridging Between Polymers and Small Molecules"
  3. Feng Jiang (UC Davis) "Novel Amphiphilic and Super Absorbent Cellulose Nanofibril Aerogels"
  4. Allison Pieja (Mango Materials) "Biodegradable Plastic Produced by Bacteria"
  5. Bor-Sen Chiou (USDA) "Torrefaction of Agricultural By-products: Effects of Temperature and Time"
  6. William Orts (USDA-ARS-WRRC) "Optimizing the Value of Agriculturally-derived Fibers Based on Their Source & Properties"
ORGANIZERS
Marty Mulvihill   
Associate Director   
Education & Outreach   
University of California   
School of Public Health   
Marc Foster   
Director of Analytics   
Micromidas   
Bill Orts   
Research Leader   
Bioproduct Chemistry & Engineering Research   
U.S. Department of Agriculture   


Solar Chemistry

Session 1: Lowcost materials for photovoltaics

This session will focus on recent advances on lowering the cost of the materials used in solar cells. Of particular interest are new low-cost synthetic methods for preparing traditional PV materials (Si, CdTe, CIGS) or new, earth-abundant materials that show promise as useful solar material (graphene/carbon nanotubes, copper oxide, iron sulfide).

Session 2: Nanomaterials for solar energy

This session will focus on new developments in nanomaterials for photovoltaics. Of particular interest are computational or experimental work on increased device efficiencies, enhanced photon management, or improved material usage in nanomaterial-based solar devices.

Presider: Professor Eric Menke

SPEAKERS

  1. Sarah Brittman (UC Berkeley) "Nanowire Solar Cells"
  2. Shanju Zhang (California Polytechnic State University) "Hybrid Organic-inorganic core-shell Nanowires Toward High Efficiency Photovoltaics"
  3. Nikolay Kornienko (UC Berkeley) "Solution Phase Growth of Indium Phosphide Nanowires and Their Application for Photoelectrochemical Energy Conversion"
  4. Rehan Kapadia (UC Berkeley) "A Direct Thin-film Path Towards Low-cost Large-area III-V Photovoltaics"
  5. Andrew Scheuermann (Stanford University) "Atomic Layer Deposited Tunnel Oxides Stabilize Silicon Photoanodes for Catalytic Water Splitting"
  6. Samuel Price (Army Research Laboratory) "Relationships Between Structure and Alkaline Stability of Imidazolium Cations for Fuel Cell Membrane Applications"
ORGANIZER
Erik Menke Assistant Professor of Chemistry   
School of Natural Sciences   
University of California, Merced   


Women Chemists

Session: Women Chemists at Various Stages of Their Careers

The California Section Women Chemists Committee invites you to hear from women chemists at various stages of their careers. We now have the opportunity to hear from a number of women chemists representing the graduate school stage up to near-retirement stage. That we can offer such a program is remarkable in itself. We have attained critical mass in several worksites, and thus invite you to spend the afternoon, learning from these diverse women chemists.

This session will be limited to invited speakers.

ORGANIZER

Elaine Yamaguchi   
Chevron, retired   

Questions about the program can be directed to Janet Gunzner-Toste and Bonnie Charpentier at programchair@wrm2013.org.

 

The 2013 Western Regional Meeting is a joint venture between
Santa Clara Valley Section,
California Section,
Western Region Board, and
American Chemical Society
All the above are 501(c)3 tax exempt organizations.

Meeting Chairs: Natalie McClure and Lee Latimer
Page Contact Information: webinfo@wrm2013.org
Page Last Modified: 4 September 2013